B Complex Ultra contains the entire spectrum of B vitamins to support adrenal and neurological functions.
It features activated forms of vitamins B2, B6, and B12; benfotiamine, a fat soluble, more physiologically
active form of thiamine; and folate as Quatrefolic®, which is proven to have greater stability, solubility, and
bioavailability over calcium salt forms of 5-MTHF.*
- Supports Carbohydrate Metabolism*
- Supports Healthy Nervous System/Adrenal/Immune Function*
- Supports Cardiovascular Health*
- Supports Healthy Mental Function and Mood*
Folate is provided as 5-methyltetrahydrofolate (5-MTHF), which bypasses metabolic steps to folate bioactivity.Despite research showing that folic acid and 5-MTHF have equivalent bioavailability and that supplementation with large doses of folic acid can “force” its conversion to the more active form, 5-MTHF may be the preferred
form to replenish folate. This may be especially applicable to those with digestive challenges or genetic variations in folate metabolism.[2-4] In this formula, 5-MTHF is provided as Quatrefolic—the glucosamine salt of 5-MTHF.
In vitro and in vivo studies have proven that Quatrefolic has greater stability, solubility, and bioavailability over calcium salt forms of 5-MTHF. Folate is stored in small amounts in red blood cells (RBC), and RBC folate has been shown to be higher after supplementation with 5-MTHF compared to folic acid and placebo. Likewise, patients given 5 mg of 5-MTHF experienced plasma levels of 5-MTHF 700% greater than patients given folic acid.*
Another unique ingredient in this formula is benfotiamine (S-benzoylthiamine O-monophosphate), a safe, fatsoluble analog of thiamine. One study showed that it not only raised blood and tissue levels of thiamine at least
five times higher than the water-soluble salt, but it also remained bioavailable after oral administration up to 3.6 times longer than thiamine salt. Benfotiamine is the most potent of a class of thiamine-derived compounds
present in small quantities in members of the Allium genus. The superiority of its biological activity compared to thiamine rests in its structure—a thiazole ring opens to allow easy diffusion through a membrane and then closes to become structurally active.*