Clinical Applications
• Supports Joint Structure and Function*
• Supports Proteoglycan Synthesis for Healthy Connective Tissue*
• Helps Protect Cartilage Cells*
• Contributes to Muscle Recovery Following Exercise*
Joint Relief Ultra features methylsulfonylmethane (MSM) blended with naturally occurring, clinically researched glucosamine sulfate and chondroitin sulfate. Combined, these three ingredients provide targeted support for healthy joint structure and function.*
Nourishing and maintaining the connective tissue (cartilage) in our joints are essential to maintaining flexibility, exercising comfortably, and recovering effectively. Three high-quality ingredients are combined in SynovX Recovery to promote joint health and assist with recovery from temporary joint discomfort due to occasional overexertion or intensive activity.*
CS b-Bioactive® Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the body. GAGs are the principal components of cartilage and synovial fluid. CS is thought to enhance joint health by supporting endogenous synthesis and preventing degradation of other joint GAGs. Oral administration of CS (800-1200 mg/d) has proven to positively influence brain response to patellar pressure, joint space width, joint comfort, and fluid accumulation.[1-5] Joint Relief Ultra provides 1200 mg of CS in the recommended four-capsule-per-day dosage.*
Glucosamine Sulfate Glucosamine is a naturally occurring amino saccharide (glucose with a nitrogen-containing amino group attached) that is a principle substrate for cartilage synthesis.[11] Research suggests that glucosamine stimulates chondrocytes (cartilage cells), supports GAG synthesis, incorporates sulfur into cartilage tissue, induces hyaluronic acid (HA) production, and modulates prostaglandin (e.g., PGE2) synthesis. [12-14]Prostaglandins (specialized hormone-like fatty acids produced in the body) regulate a wide variety of bodily functions, including cytokine production and balance. Glucosamine sulfate was found to inhibit the release of PGE2, the activity of NF-kappaB, and the synthesis of COX-2 enzymes in human chondrocytes.*[15]
Methylsulfonylmethane (MSM) As an organosulfur compound, MSM is thought to primarily benefit joint tissues by delivering sulfur. Sulfur helps maintain the strength and structure of connective tissue by forming cross-linkages through disulfide bonds—such as those found in GAGs.[22] One joint study shows that glucosamine and MSM achieve better results when combined than when administered individually.*[23]Research suggests that MSM may reduce joint tissue damage triggered by free radicals and support muscle recovery after exercise through its antioxidant capacity. Though relatively high doses of MSM were used in exercise studies, the one gram provided in two servings of Joint Relief Ultra can contribute to MSM dosing for exercise recovery.*[24-26]
Does Not Contain
Wheat, gluten, corn, yeast, soy, dairy products, fish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives